CD3 antibody (PerCP)

Catalog No. ABIN7674191

This Rat Monoclonal antibody specifically detects CD3 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CD3 antibody (PerCP) (ABIN7674191)

Target: CD3

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD3 antibody is conjugated to PerCP

Application: Flow Cytometry (FACS)

Clone: 17A2

Product Details anti-CD3 Antibody (PerCP)

Purpose: PerCP Anti-Mouse CD3 Antibody

Purification: 0

Purity: 0

Isotype: IgG2b, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD3

Target: CD3

Alternative Name: CD3

Background:

Synonyms: CD3|CD3E/D/G/Z|CD3e/d/g/z|T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain

Background: CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Molecular Weight: 0

Gene ID: 12502

UniProt: P04235, P11942, P22646, P24161

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway